2wv3: Difference between revisions

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<StructureSection load='2wv3' size='340' side='right'caption='[[2wv3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2wv3' size='340' side='right'caption='[[2wv3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WV3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WV3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wv3 OCA], [https://pdbe.org/2wv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2wv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wv3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wv3 OCA], [https://pdbe.org/2wv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wv3 RCSB], [https://www.ebi.ac.uk/pdbsum/2wv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wv3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NPTN_RAT NPTN_RAT]] Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity.<ref>PMID:10759566</ref> <ref>PMID:16925595</ref> <ref>PMID:19952283</ref>
[https://www.uniprot.org/uniprot/NPTN_RAT NPTN_RAT] Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity.<ref>PMID:10759566</ref> <ref>PMID:16925595</ref> <ref>PMID:19952283</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wv3_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wv3_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Berezin, V]]
[[Category: Rattus norvegicus]]
[[Category: Bock, E]]
[[Category: Berezin V]]
[[Category: Gajhede, M]]
[[Category: Bock E]]
[[Category: Kastrup, J S]]
[[Category: Gajhede M]]
[[Category: Owczarek, S]]
[[Category: Kastrup JS]]
[[Category: Soroka, V]]
[[Category: Owczarek S]]
[[Category: Alternative splicing]]
[[Category: Soroka V]]
[[Category: Cell adhesion]]
[[Category: Cell membrane]]
[[Category: Disulfide bond]]
[[Category: Glycoprotein]]
[[Category: Igcam]]
[[Category: Immunoglobulin domain]]
[[Category: Membrane]]
[[Category: Transmembrane]]
Retrieved from "https://proteopedia.org/2wv3"