6gqd: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
Line 1: Line 1:


==Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L==
==Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L==
<StructureSection load='6gqd' size='340' side='right' caption='[[6gqd]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
<StructureSection load='6gqd' size='340' side='right'caption='[[6gqd]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6gqd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GQD FirstGlance]. <br>
<table><tr><td colspan='2'>[[6gqd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GQD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.523&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5in3|5in3]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose--hexose-1-phosphate_uridylyltransferase UDP-glucose--hexose-1-phosphate uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.12 2.7.7.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gqd OCA], [https://pdbe.org/6gqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gqd RCSB], [https://www.ebi.ac.uk/pdbsum/6gqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gqd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gqd OCA], [http://pdbe.org/6gqd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gqd RCSB], [http://www.ebi.ac.uk/pdbsum/6gqd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gqd ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/GALT_HUMAN GALT_HUMAN]] Classic galactosemia. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/GALT_HUMAN GALT_HUMAN] Classic galactosemia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/GALT_HUMAN GALT_HUMAN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: UDP-glucose--hexose-1-phosphate uridylyltransferase]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C]]
[[Category: Large Structures]]
[[Category: Bezerra, G A]]
[[Category: Arrowsmith C]]
[[Category: Bountra, C]]
[[Category: Bezerra GA]]
[[Category: Burgess-Brown, N]]
[[Category: Bountra C]]
[[Category: Delft, F von]]
[[Category: Burgess-Brown N]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Fairhead, M]]
[[Category: Fairhead M]]
[[Category: Kopec, J]]
[[Category: Kopec J]]
[[Category: Structural genomic]]
[[Category: Strain-Damerell C]]
[[Category: Strain-Damerell, C]]
[[Category: Yue WW]]
[[Category: Yue, W W]]
[[Category: Zhang M]]
[[Category: Zhang, M]]
[[Category: Von Delft F]]
[[Category: Crystal epitope]]
[[Category: Glucose-1-phosphate]]
[[Category: Sgc]]
[[Category: Transferase]]
[[Category: Uridine monophosphate]]

Latest revision as of 09:59, 23 October 2024

Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L

6gqd, resolution 1.52Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA