3oai

Crystal structure of the extra-cellular domain of human myelin protein zero

spinqualitylabelsall models 3oai, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3oai is a 2 chain structure with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: GLC, PRD_900001 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease MYP0_HUMAN Palmoplantar keratoderma-hereditary motor and sensory neuropathy syndrome;Autosomal dominant intermediate Charcot-Marie-Tooth disease type D;Autosomal dominant Charcot-Marie-Tooth disease type 2I;Roussy-Levy syndrome;Autosomal dominant intermediate Charcot-Marie-Tooth disease with neuropathic pain;Dejerine-Sottas syndrome;Charcot-Marie-Tooth disease type 1B;Autosomal dominant Charcot-Marie-Tooth disease type 2J. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease may be caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function MALE_ECOLI Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.MYP0_HUMAN Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.

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