3uaf: Difference between revisions

<table><tr><td colspan='2'>[[3uaf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UAF FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uaf OCA], [https://pdbe.org/3uaf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uaf RCSB], [https://www.ebi.ac.uk/pdbsum/3uaf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uaf ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TTR52_CAEEL TTR52_CAEEL] Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1. Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner. Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells. Does not affect the phosphatidylserine externalization in living cells. May play a role in mediating transfer of phosphatidylserine from phosphatidylserine vesicles to ced-1 bearing phagocytes or alternatively result in the activation of a phosphatidylserine transporter in the phagocyte that promotes phosphatidylserine externalization.<ref>PMID:20526330</ref> <ref>PMID:22727700</ref> <ref>PMID:22727702</ref>  

[[Category: Caenorhabditis elegans]]

[[Category: Kang YY]]

[[Category: Liang HH]]

[[Category: Liu B]]

[[Category: Liu QW]]

[[Category: Liu YF]]

[[Category: Wang XC]]

[[Category: Zhao DF]]