7v63: Difference between revisions

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<StructureSection load='7v63' size='340' side='right'caption='[[7v63]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
<StructureSection load='7v63' size='340' side='right'caption='[[7v63]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7v63]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V63 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V63 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.906&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v63 OCA], [https://pdbe.org/7v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v63 RCSB], [https://www.ebi.ac.uk/pdbsum/7v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v63 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v63 OCA], [https://pdbe.org/7v63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v63 RCSB], [https://www.ebi.ac.uk/pdbsum/7v63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v63 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
 
[[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN]] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
==See Also==
*[[Urokinase plasminogen activator surface receptor 3D structures|Urokinase plasminogen activator surface receptor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Huang, M]]
[[Category: Huang M]]
[[Category: Yuan, C]]
[[Category: Yuan C]]
[[Category: Gpi-anchored protein]]
[[Category: Immune system]]

Latest revision as of 11:44, 30 October 2024

Structure of dimeric uPAR at low pH

7v63, resolution 2.91Å

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