8ua3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM Structure of FBOX22-BACH1BTB== | |||
<StructureSection load='8ua3' size='340' side='right'caption='[[8ua3]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ua3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UA3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ua3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ua3 OCA], [https://pdbe.org/8ua3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ua3 RCSB], [https://www.ebi.ac.uk/pdbsum/8ua3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ua3 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Cao | == Function == | ||
[[Category: Zheng | [https://www.uniprot.org/uniprot/FBX22_HUMAN FBX22_HUMAN] Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.<ref>PMID:22972877</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao S]] | |||
[[Category: Shi H]] | |||
[[Category: Zheng N]] | |||