1u47: Difference between revisions

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[[Image:1u47.gif|left|200px]]
[[Image:1u47.gif|left|200px]]


{{Structure
<!--
|PDB= 1u47 |SIZE=350|CAPTION= <scene name='initialview01'>1u47</scene>, resolution 2.00&Aring;
The line below this paragraph, containing "STRUCTURE_1u47", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=8OG:8-OXO-2&#39;-DEOXY-GUANOSINE-5&#39;-MONOPHOSPHATE'>8OG</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1u47| PDB=1u47  | SCENE= }}  
|RELATEDENTRY=[[1u45|1U45]], [[1u48|1U48]], [[1u49|1U49]], [[1u4b|1U4B]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u47 OCA], [http://www.ebi.ac.uk/pdbsum/1u47 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u47 RCSB]</span>
}}


'''cytosine-8-Oxoguanine base pair at the polymerase active site'''
'''cytosine-8-Oxoguanine base pair at the polymerase active site'''
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==About this Structure==
==About this Structure==
1U47 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U47 OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U47 OCA].  


==Reference==
==Reference==
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase., Hsu GW, Ober M, Carell T, Beese LS, Nature. 2004 Sep 9;431(7005):217-21. Epub 2004 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15322558 15322558]
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase., Hsu GW, Ober M, Carell T, Beese LS, Nature. 2004 Sep 9;431(7005):217-21. Epub 2004 Aug 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15322558 15322558]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Protein complex]]
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
[[Category: Carell, T.]]
[[Category: Carell, T.]]
Line 31: Line 26:
[[Category: Ober, M.]]
[[Category: Ober, M.]]
[[Category: 8oxoguanine]]
[[Category: 8oxoguanine]]
[[Category: dna lesion]]
[[Category: Dna lesion]]
[[Category: dna polymerase i]]
[[Category: Dna polymerase i]]
[[Category: dna replication]]
[[Category: Dna replication]]
[[Category: klenow fragment]]
[[Category: Klenow fragment]]
[[Category: protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: translation replication]]
[[Category: Translation replication]]
 
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