3it7: Difference between revisions

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<StructureSection load='3it7' size='340' side='right'caption='[[3it7]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='3it7' size='340' side='right'caption='[[3it7]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3it7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IT7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3it7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IT7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3it5|3it5]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3it7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3it7 OCA], [https://pdbe.org/3it7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3it7 RCSB], [https://www.ebi.ac.uk/pdbsum/3it7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3it7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3it7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3it7 OCA], [https://pdbe.org/3it7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3it7 RCSB], [https://www.ebi.ac.uk/pdbsum/3it7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3it7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/LASA_PSEAE LASA_PSEAE]] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.  
[https://www.uniprot.org/uniprot/LASA_PSEAE LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/3it7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/it/3it7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Conners, R]]
[[Category: Conners R]]
[[Category: Gamblin, S J]]
[[Category: Gamblin SJ]]
[[Category: Murphy, L M]]
[[Category: Murphy LM]]
[[Category: Sessions, R B]]
[[Category: Sessions RB]]
[[Category: Spencer, J]]
[[Category: Spencer J]]
[[Category: Beta-protein]]
[[Category: Cell membrane]]
[[Category: Cell outer membrane]]
[[Category: Hydrolase]]
[[Category: M23]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Metallopeptidase]]
[[Category: Metalloprotease]]
[[Category: Protease]]
[[Category: Zymogen]]