3s32: Difference between revisions
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<StructureSection load='3s32' size='340' side='right'caption='[[3s32]], [[Resolution|resolution]] 2.45Å' scene=''> | <StructureSection load='3s32' size='340' side='right'caption='[[3s32]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3s32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3s32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S32 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s32 OCA], [https://pdbe.org/3s32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s32 RCSB], [https://www.ebi.ac.uk/pdbsum/3s32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s32 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s32 OCA], [https://pdbe.org/3s32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s32 RCSB], [https://www.ebi.ac.uk/pdbsum/3s32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s32 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ASH2L_HUMAN ASH2L_HUMAN] Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.<ref>PMID:12670868</ref> <ref>PMID:19556245</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Avdic | [[Category: Avdic V]] | ||
[[Category: Blais | [[Category: Blais A]] | ||
[[Category: Brand | [[Category: Brand M]] | ||
[[Category: Brunzelle | [[Category: Brunzelle JS]] | ||
[[Category: Chaturvedi | [[Category: Chaturvedi C-P]] | ||
[[Category: Couture | [[Category: Couture J-F]] | ||
[[Category: Lanouette | [[Category: Lanouette S]] | ||
[[Category: Sarvan | [[Category: Sarvan S]] | ||
[[Category: Tremblay | [[Category: Tremblay V]] | ||
[[Category: Zhang | [[Category: Zhang P]] | ||
