5ubp: Difference between revisions

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<StructureSection load='5ubp' size='340' side='right'caption='[[5ubp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5ubp' size='340' side='right'caption='[[5ubp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ubp]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UBP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UBP FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ubp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_RM11-1a Saccharomyces cerevisiae RM11-1a] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UBP FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ubp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ubp OCA], [http://pdbe.org/5ubp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ubp RCSB], [http://www.ebi.ac.uk/pdbsum/5ubp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ubp ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ubp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ubp OCA], [https://pdbe.org/5ubp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ubp RCSB], [https://www.ebi.ac.uk/pdbsum/5ubp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ubp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SEM1_YEAST SEM1_YEAST]] Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Associates also with the TREX-2 complex that is required for transcription-coupled mRNA export, and the COP9 signalosome, which is involved in deneddylation.<ref>PMID:19289793</ref> <ref>PMID:15117943</ref> [[http://www.uniprot.org/uniprot/THP1_YEAST THP1_YEAST]] Component of the SAC3-THP1 complex, which functions in transcription-coupled mRNA export from the nucleus to the cytoplasm. SAC3-THP1 functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket. THP1 binds to RNA in vitro.<ref>PMID:11139493</ref> <ref>PMID:12411502</ref> <ref>PMID:12702719</ref> 
[https://www.uniprot.org/uniprot/SEM1_YEAST SEM1_YEAST] Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Associates also with the TREX-2 complex that is required for transcription-coupled mRNA export, and the COP9 signalosome, which is involved in deneddylation.<ref>PMID:19289793</ref> <ref>PMID:15117943</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gordon, J]]
[[Category: Saccharomyces cerevisiae RM11-1a]]
[[Category: Stewart, M]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Tpr repeat]]
[[Category: Gordon J]]
[[Category: Transcription]]
[[Category: Stewart M]]
[[Category: Trex2 complex]]
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