8sjx: Difference between revisions
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==Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (2SM:1Chol)== | |||
<StructureSection load='8sjx' size='340' side='right'caption='[[8sjx]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8sjx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SJX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=HWP:[(~{E},2~{S},3~{R})-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl]+2-(trimethylazaniumyl)ethyl+phosphate'>HWP</scene></td></tr> | ||
[[Category: Chiu | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8sjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8sjx OCA], [https://pdbe.org/8sjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8sjx RCSB], [https://www.ebi.ac.uk/pdbsum/8sjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8sjx ProSAT]</span></td></tr> | ||
[[Category: Walz | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MIP_SHEEP MIP_SHEEP] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:15141214</ref> <ref>PMID:15351655</ref> <ref>PMID:20389283</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Ovis aries]] | |||
[[Category: Chiu P-L]] | |||
[[Category: Walz T]] | |||
Latest revision as of 14:52, 6 November 2024
Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (2SM:1Chol)
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