How to predict structures with AlphaFold: Difference between revisions
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* New in 2024<ref name="combfold">PMID: 38326495</ref>: [https://neurosnap.ai/service/CombFold CombFold] predicts the structures of large protein complexes from subunit sequences using AlphaFold Multimer paired with a cominatorial method to assemble subunits. From Shor and Schneidman-Duhovny<ref name="combfold" />. | * New in 2024<ref name="combfold">PMID: 38326495</ref>: [https://neurosnap.ai/service/CombFold CombFold] predicts the structures of large protein complexes from subunit sequences using AlphaFold Multimer paired with a cominatorial method to assemble subunits. From Shor and Schneidman-Duhovny<ref name="combfold" />. | ||
* New in 2022<ref name="colabfold">PMID: 35637307</ref>: [https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb ColabFold AlphaFold2_advanced]. Predicts homo- and hetero-multimers using methods from the Steinegger team<ref name="colabfold" /><ref name="colabfold2024">PMID: 39402428</ref>, before AlphaFold-multimer<ref name="afmultimer">[https://www.biorxiv.org/content/10.1101/2021.10.04.463034v1.full Protein complex prediction with AlphaFold-Multimer], Preprint, Evans et al. 2021.</ref> was available. Does NOT use templates. | * New in 2022<ref name="colabfold">PMID: 35637307</ref>: [https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb ColabFold AlphaFold2_advanced]. Predicts homo- and hetero-multimers using methods from the Steinegger/Mirdita team<ref name="colabfold" /><ref name="colabfold2024">PMID: 39402428</ref>, before AlphaFold-multimer<ref name="afmultimer">[https://www.biorxiv.org/content/10.1101/2021.10.04.463034v1.full Protein complex prediction with AlphaFold-Multimer], Preprint, Evans et al. 2021.</ref> was available. Does NOT use templates. | ||
*New in 2022<ref name="alphafill">PMID: 36424442</ref>: [https://alphafill.eu/ AlphaFill] “transplants” missing ligands, cofactors and (metal) ions into AlphaFold models. From the Perrakis team<ref name="alphafill" />. | *New in 2022<ref name="alphafill">PMID: 36424442</ref>: [https://alphafill.eu/ AlphaFill] “transplants” missing ligands, cofactors and (metal) ions into AlphaFold models. From the Perrakis team<ref name="alphafill" />. | ||