3e0j: Difference between revisions

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<StructureSection load='3e0j' size='340' side='right'caption='[[3e0j]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3e0j' size='340' side='right'caption='[[3e0j]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3e0j]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E0J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3E0J FirstGlance]. <br>
<table><tr><td colspan='2'>[[3e0j]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E0J FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3e0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e0j OCA], [http://pdbe.org/3e0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e0j RCSB], [http://www.ebi.ac.uk/pdbsum/3e0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e0j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e0j OCA], [https://pdbe.org/3e0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e0j RCSB], [https://www.ebi.ac.uk/pdbsum/3e0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e0j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPOD2_HUMAN DPOD2_HUMAN]] The function of the small subunit is not yet clear. [[http://www.uniprot.org/uniprot/DPOD3_HUMAN DPOD3_HUMAN]] Required for optimal DNA polymerase delta activity.<ref>PMID:10219083</ref> <ref>PMID:10852724</ref> <ref>PMID:16510448</ref> 
[https://www.uniprot.org/uniprot/DPOD2_HUMAN DPOD2_HUMAN] The function of the small subunit is not yet clear.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e0/3e0j_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e0/3e0j_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Babayeva, N D]]
[[Category: Babayeva ND]]
[[Category: Baranovskiy, A G]]
[[Category: Baranovskiy AG]]
[[Category: Pavlov, Y I]]
[[Category: Pavlov YI]]
[[Category: Tahirov, T H]]
[[Category: Tahirov TH]]
[[Category: Vassylyev, D G]]
[[Category: Vassylyev DG]]
[[Category: Dna polymerase delta]]
[[Category: Dna replication]]
[[Category: Dna-directed dna polymerase]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleus]]
[[Category: P50 subunit]]
[[Category: P66 subunit]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Transferase]]
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