6o4p: Difference between revisions

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<StructureSection load='6o4p' size='340' side='right'caption='[[6o4p]], [[Resolution|resolution]] 3.43&Aring;' scene=''>
<StructureSection load='6o4p' size='340' side='right'caption='[[6o4p]], [[Resolution|resolution]] 3.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6o4p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O4P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6O4P FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O4P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.429&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL11RA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6o4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o4p OCA], [http://pdbe.org/6o4p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6o4p RCSB], [http://www.ebi.ac.uk/pdbsum/6o4p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6o4p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o4p OCA], [https://pdbe.org/6o4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o4p RCSB], [https://www.ebi.ac.uk/pdbsum/6o4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o4p ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/I11RA_HUMAN I11RA_HUMAN]] Craniosynostosis-dental anomalies. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[[http://www.uniprot.org/uniprot/I11RA_HUMAN I11RA_HUMAN]] Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.<ref>PMID:21741611</ref> 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6o4p" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6o4p" style="background-color:#fffaf0;"></div>
==See Also==
*[[Interleukin receptor 3D structures|Interleukin receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aizel, K]]
[[Category: Aizel K]]
[[Category: Griffin, M D.W]]
[[Category: Griffin MDW]]
[[Category: Metcalfe, R D]]
[[Category: Metcalfe RD]]
[[Category: Cytokine]]
[[Category: Interleukin]]
[[Category: Protein binding]]
[[Category: Receptor]]
Retrieved from "https://proteopedia.org/6o4p"