3osl: Difference between revisions

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<StructureSection load='3osl' size='340' side='right'caption='[[3osl]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
<StructureSection load='3osl' size='340' side='right'caption='[[3osl]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3osl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Rhibu Rhibu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OSL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3osl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Rhipicephalus_bursa Rhipicephalus bursa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OSL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3d4u|3d4u]], [[3dgv|3dgv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_U Carboxypeptidase U], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.20 3.4.17.20] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3osl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3osl OCA], [https://pdbe.org/3osl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3osl RCSB], [https://www.ebi.ac.uk/pdbsum/3osl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3osl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3osl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3osl OCA], [http://pdbe.org/3osl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3osl RCSB], [http://www.ebi.ac.uk/pdbsum/3osl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3osl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CBPB2_BOVIN CBPB2_BOVIN]] Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.  
[https://www.uniprot.org/uniprot/CBPB2_BOVIN CBPB2_BOVIN] Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/3osl_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/os/3osl_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Carboxypeptidase U]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rhibu]]
[[Category: Rhipicephalus bursa]]
[[Category: Arolas, J L]]
[[Category: Arolas JL]]
[[Category: Aviles, F X]]
[[Category: Aviles FX]]
[[Category: Enghild, J J]]
[[Category: Enghild JJ]]
[[Category: Gomis-Ruth, F X]]
[[Category: Gomis-Ruth FX]]
[[Category: Otzen, D]]
[[Category: Otzen D]]
[[Category: Petersen, S V]]
[[Category: Petersen SV]]
[[Category: Sanglas, L]]
[[Category: Sanglas L]]
[[Category: Schar, C]]
[[Category: Schar C]]
[[Category: Valnickova, Z]]
[[Category: Valnickova Z]]
[[Category: Alpha/beta-hydrolase-related fold]]
[[Category: Blood]]
[[Category: Coagulation]]
[[Category: Fibrinolysis]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
Retrieved from "https://proteopedia.org/3osl"