8t1w: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8t1w is ~~ON HOLD until Paper Publication~~

==Crystal structure of orphan G protein-coupled receptor 6 with bound CVN424==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8t1w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T1W OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8T1W FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.49Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=X7T:1-{2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-{[(3R)-oxolan-3-yl]amino}-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl}ethan-1-one'>X7T</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8t1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t1w OCA], [https://pdbe.org/8t1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t1w RCSB], [https://www.ebi.ac.uk/pdbsum/8t1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t1w ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/GPR6_HUMAN GPR6_HUMAN] Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).

__TOC__

</StructureSection>

[[Category: Escherichia coli]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Barekatain M]]

[[Category: Beresford M]]

[[Category: Bliesath J]]

[[Category: Brice N]]

[[Category: Carlson L]]

[[Category: Cherezov V]]

[[Category: Han GW]]

[[Category: Hua T]]

[[Category: Johansson L]]

[[Category: Katritch V]]

[[Category: Lam JH]]

[[Category: Liu Z]]

[[Category: Lutomski C]]

[[Category: Monenschein H]]

[[Category: Murphy S]]

[[Category: Popov P]]

[[Category: Robinson CV]]

[[Category: Russo J]]

[[Category: Sadybekov AV]]

[[Category: Saikatendu KS]]

[[Category: Schiffer HH]]

[[Category: Sun H]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8t1w is ON HOLD  until Paper Publication
+==Crystal structure of orphan G protein-coupled receptor 6 with bound CVN424==
+<StructureSection load='8t1w' size='340' side='right'caption='[[8t1w]], [[Resolution|resolution]] 3.49&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8t1w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T1W FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.49&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=X7T:1-{2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-{[(3R)-oxolan-3-yl]amino}-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl}ethan-1-one'>X7T</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t1w OCA], [https://pdbe.org/8t1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t1w RCSB], [https://www.ebi.ac.uk/pdbsum/8t1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t1w ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/GPR6_HUMAN GPR6_HUMAN] Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Barekatain M]]
+[[Category: Beresford M]]
+[[Category: Bliesath J]]
+[[Category: Brice N]]
+[[Category: Carlson L]]
+[[Category: Cherezov V]]
+[[Category: Han GW]]
+[[Category: Hua T]]
+[[Category: Johansson L]]
+[[Category: Katritch V]]
+[[Category: Lam JH]]
+[[Category: Liu Z]]
+[[Category: Lutomski C]]
+[[Category: Monenschein H]]
+[[Category: Murphy S]]
+[[Category: Popov P]]
+[[Category: Robinson CV]]
+[[Category: Russo J]]
+[[Category: Sadybekov AV]]
+[[Category: Saikatendu KS]]
+[[Category: Schiffer HH]]
+[[Category: Sun H]]