9dzq: Difference between revisions
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==CryoEM structure of the human antibodies PIV3HN-05 and PIV3HN-13 in complex with the parainfluenza virus hemagglutinin-neuraminidase protein== | |||
<StructureSection load='9dzq' size='340' side='right'caption='[[9dzq]], [[Resolution|resolution]] 3.57Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9dzq]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_respirovirus_3 Human respirovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DZQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DZQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.57Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dzq OCA], [https://pdbe.org/9dzq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dzq RCSB], [https://www.ebi.ac.uk/pdbsum/9dzq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dzq ProSAT]</span></td></tr> | ||
[[Category: Miller | </table> | ||
[[Category: Mousa | == Function == | ||
[https://www.uniprot.org/uniprot/Q81080_PI3H4 Q81080_PI3H4] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.[ARBA:ARBA00025476] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human respirovirus 3]] | |||
[[Category: Large Structures]] | |||
[[Category: Miller RJ]] | |||
[[Category: Mousa JJ]] | |||
Latest revision as of 06:20, 4 December 2024
CryoEM structure of the human antibodies PIV3HN-05 and PIV3HN-13 in complex with the parainfluenza virus hemagglutinin-neuraminidase protein
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