9g2y: Difference between revisions
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==Cryo-EM structure of IrtAB in inward-facing state under turnover conditions in LMNG== | |||
<StructureSection load='9g2y' size='340' side='right'caption='[[9g2y]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9g2y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_thermoresistibile_ATCC_19527 Mycolicibacterium thermoresistibile ATCC 19527]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9G2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9G2Y FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9g2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9g2y OCA], [https://pdbe.org/9g2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9g2y RCSB], [https://www.ebi.ac.uk/pdbsum/9g2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9g2y ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IRTA_MYCT3 IRTA_MYCT3] Part of the ABC transporter complex IrtAB involved in the import of iron-bound mycobactin (Fe-MBT) and carboxymycobactin (Fe-cMBT) (PubMed:32296173). Has a preference for Fe-MBT over Fe-cMBT (PubMed:32296173). Mycobactins are then reduced by the siderophore interaction domain to facilitate iron release in the bacterial cell (PubMed:32296173). Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (PubMed:32296173).<ref>PMID:32296173</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycolicibacterium thermoresistibile ATCC 19527]] | |||
[[Category: Gonda I]] | |||
[[Category: Seeger MA]] | |||
Latest revision as of 06:33, 18 December 2024
Cryo-EM structure of IrtAB in inward-facing state under turnover conditions in LMNG
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