Semaglutide: Difference between revisions
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[[Image:Semaglutide Artwork.PNG|thumb|Semaglutide [[4zgm]] (scroll down for interactive figures)]] | |||
Semaglutide is an analog of the GLP-1 (glucagon-like peptide 1) hormone. It acts as an agonist to the GLP-1 receptor and is used as drug to manage diabetes. Its use has been growing as a weight-loss medication, and potential benefits across a wide range of diseases is currently studied. | Semaglutide is an analog of the GLP-1 (glucagon-like peptide 1) hormone. It acts as an agonist to the GLP-1 receptor and is used as drug to manage diabetes. Its use has been growing as a weight-loss medication, and potential benefits across a wide range of diseases is currently studied. | ||
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Semaglutide was discovered <ref name = "discovery">PMID:26308095</ref> in an effort to increase the lifetime of a once-a-day medication called Liraglutide. It is derived from the [[GLP-1]] hormone with modifications described below. | Semaglutide was discovered <ref name = "discovery">PMID:26308095</ref> in an effort to increase the lifetime of a once-a-day medication called Liraglutide. It is derived from the [[GLP-1]] hormone with modifications described below. | ||
==Structure and binding to GLP-1R== | ==Structure and binding to GLP-1R== | ||
