2p8w: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2p8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P8W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2p8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P8W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k5x|1k5x]], [[1k5y|1k5y]], [[2p8x|2p8x]], [[2p8y|2p8y]], [[2p8z|2p8z]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8w OCA], [https://pdbe.org/2p8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p8w RCSB], [https://www.ebi.ac.uk/pdbsum/2p8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p8w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8w OCA], [https://pdbe.org/2p8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p8w RCSB], [https://www.ebi.ac.uk/pdbsum/2p8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p8w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EFTU2_THET8 EFTU2_THET8]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
[https://www.uniprot.org/uniprot/EF2_YEAST EF2_YEAST]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/2p8w_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/2p8w_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Andersen, G R]]
[[Category: Andersen GR]]
[[Category: Frank, J]]
[[Category: Frank J]]
[[Category: Merrill, A R]]
[[Category: Merrill AR]]
[[Category: Nilsson, J]]
[[Category: Nilsson J]]
[[Category: Nissen, P]]
[[Category: Nissen P]]
[[Category: Taylor, D J]]
[[Category: Taylor DJ]]
[[Category: 80s ribosome]]
[[Category: Elongation]]
[[Category: Gtpase]]
[[Category: Translation]]
[[Category: Translocation]]

Latest revision as of 09:47, 25 December 2024

Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction

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