9izf: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9izf is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of LPA1-Gi complex with LPA==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9izf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IZF OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9IZF FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.14Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NKP:(2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL+(9E)-OCTADEC-9-ENOATE'>NKP</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9izf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9izf OCA], [https://pdbe.org/9izf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9izf RCSB], [https://www.ebi.ac.uk/pdbsum/9izf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9izf ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Escherichia coli]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Synthetic construct]]

[[Category: Fujiyoshi Y]]

[[Category: Hiroaki Y]]

[[Category: Kamegawa A]]

[[Category: Nishikawa K]]

[[Category: Suzuki H]]

[[Category: Suzuki S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9izf is ON HOLD  until Paper Publication
+==Cryo-EM structure of LPA1-Gi complex with LPA==
+<StructureSection load='9izf' size='340' side='right'caption='[[9izf]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9izf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IZF FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.14&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NKP:(2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL+(9E)-OCTADEC-9-ENOATE'>NKP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9izf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9izf OCA], [https://pdbe.org/9izf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9izf RCSB], [https://www.ebi.ac.uk/pdbsum/9izf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9izf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Synthetic construct]]
+[[Category: Fujiyoshi Y]]
+[[Category: Hiroaki Y]]
+[[Category: Kamegawa A]]
+[[Category: Nishikawa K]]
+[[Category: Suzuki H]]
+[[Category: Suzuki S]]