8rj0: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8rj0 is ~~ON HOLD until Paper Publication~~

==Crystal structure of mutant aspartase from Bacillus sp. YM55-1 in the closed loop conformation==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8rj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._YM55-1 Bacillus sp. YM55-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RJ0 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8RJ0 FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8rj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rj0 OCA], [https://pdbe.org/8rj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rj0 RCSB], [https://www.ebi.ac.uk/pdbsum/8rj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rj0 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ASPA_BACSP ASPA_BACSP] Catalyzes the reversible conversion of L-aspartate to fumarate and ammonia (PubMed:10334861, PubMed:10712618, PubMed:18844200, PubMed:19490103). Is highly specific for L-aspartate in the deamination reaction, and cannot use alternative substrates such as D-aspartic acid, alpha-methyl-DL-aspartic acid, beta-methyl-DL-aspartic acid or L-glutamate (PubMed:18844200). In the reverse reaction, alternative nucleophiles (such as hydroxylamine, hydrazine, methoxylamine and methylamine) can replace ammonia in vitro, leading to the formation of N-substituted aspartic acid derivatives (PubMed:18844200).<ref>PMID:10334861</ref> <ref>PMID:10712618</ref> <ref>PMID:18844200</ref> <ref>PMID:19490103</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Bacillus sp. YM55-1]]

[[Category: Large Structures]]

[[Category: Capra N]]

[[Category: Janssen DB]]

[[Category: Thunnissen AMWH]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8rj0 is ON HOLD  until Paper Publication
+==Crystal structure of mutant aspartase from Bacillus sp. YM55-1 in the closed loop conformation==
+<StructureSection load='8rj0' size='340' side='right'caption='[[8rj0]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8rj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._YM55-1 Bacillus sp. YM55-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RJ0 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rj0 OCA], [https://pdbe.org/8rj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rj0 RCSB], [https://www.ebi.ac.uk/pdbsum/8rj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rj0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ASPA_BACSP ASPA_BACSP] Catalyzes the reversible conversion of L-aspartate to fumarate and ammonia (PubMed:10334861, PubMed:10712618, PubMed:18844200, PubMed:19490103). Is highly specific for L-aspartate in the deamination reaction, and cannot use alternative substrates such as D-aspartic acid, alpha-methyl-DL-aspartic acid, beta-methyl-DL-aspartic acid or L-glutamate (PubMed:18844200). In the reverse reaction, alternative nucleophiles (such as hydroxylamine, hydrazine, methoxylamine and methylamine) can replace ammonia in vitro, leading to the formation of N-substituted aspartic acid derivatives (PubMed:18844200).<ref>PMID:10334861</ref> <ref>PMID:10712618</ref> <ref>PMID:18844200</ref> <ref>PMID:19490103</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bacillus sp. YM55-1]]
+[[Category: Large Structures]]
+[[Category: Capra N]]
+[[Category: Janssen DB]]
+[[Category: Thunnissen AMWH]]