1uwb: Difference between revisions

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[[Image:1uwb.jpg|left|200px]]
[[Image:1uwb.jpg|left|200px]]


{{Structure
<!--
|PDB= 1uwb |SIZE=350|CAPTION= <scene name='initialview01'>1uwb</scene>, resolution 3.2&Aring;
The line below this paragraph, containing "STRUCTURE_1uwb", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=TBO:5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE'>TBO</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1uwb| PDB=1uwb  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwb OCA], [http://www.ebi.ac.uk/pdbsum/1uwb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1uwb RCSB]</span>
}}


'''TYR 181 CYS HIV-1 RT/8-CL TIBO'''
'''TYR 181 CYS HIV-1 RT/8-CL TIBO'''
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Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant., Das K, Ding J, Hsiou Y, Clark AD Jr, Moereels H, Koymans L, Andries K, Pauwels R, Janssen PA, Boyer PL, Clark P, Smith RH Jr, Kroeger Smith MB, Michejda CJ, Hughes SH, Arnold E, J Mol Biol. 1996 Dec 20;264(5):1085-100. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000632 9000632]
Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant., Das K, Ding J, Hsiou Y, Clark AD Jr, Moereels H, Koymans L, Andries K, Pauwels R, Janssen PA, Boyer PL, Clark P, Smith RH Jr, Kroeger Smith MB, Michejda CJ, Hughes SH, Arnold E, J Mol Biol. 1996 Dec 20;264(5):1085-100. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000632 9000632]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus type 1 (isolate 12)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
Line 31: Line 27:
[[Category: Ding, J.]]
[[Category: Ding, J.]]
[[Category: Hsiou, Y.]]
[[Category: Hsiou, Y.]]
[[Category: aid]]
[[Category: Aid]]
[[Category: aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: drug-resistant mutant]]
[[Category: Drug-resistant mutant]]
[[Category: endonuclease]]
[[Category: Endonuclease]]
[[Category: hydrolase]]
[[Category: Hydrolase]]
[[Category: polyprotein]]
[[Category: Polyprotein]]
[[Category: rna-directed dna polymerase]]
[[Category: Rna-directed dna polymerase]]
[[Category: tyr181cys hiv-1 rt/8-cl tibo]]
[[Category: Tyr181cys hiv-1 rt/8-cl tibo]]
 
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