7yri: Difference between revisions
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<StructureSection load='7yri' size='340' side='right'caption='[[7yri]], [[Resolution|resolution]] 2.61Å' scene=''> | <StructureSection load='7yri' size='340' side='right'caption='[[7yri]], [[Resolution|resolution]] 2.61Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7yri]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[7yri]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YRI FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yri OCA], [https://pdbe.org/7yri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yri RCSB], [https://www.ebi.ac.uk/pdbsum/7yri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yri ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yri OCA], [https://pdbe.org/7yri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yri RCSB], [https://www.ebi.ac.uk/pdbsum/7yri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yri ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SAMTR_DROME SAMTR_DROME] S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling (PubMed:29123071, PubMed:35776786). Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1 (PubMed:29123071, PubMed:35776786). Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.[HAMAP-Rule:MF_03044]<ref>PMID:29123071</ref> <ref>PMID:35776786</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Li XZ]] | [[Category: Li XZ]] | ||
[[Category: Wen YN]] | [[Category: Wen YN]] | ||
[[Category: Zhang H]] | [[Category: Zhang H]] | ||
Latest revision as of 06:30, 29 January 2025
S-adenosylmethionine sensor upstream of mTORC1
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