8zdc: Difference between revisions

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'''Unreleased structure'''


The entry 8zdc is ON HOLD  until Paper Publication
==Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3==
 
<StructureSection load='8zdc' size='340' side='right'caption='[[8zdc]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8zdc]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZDC FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zdc OCA], [https://pdbe.org/8zdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zdc RCSB], [https://www.ebi.ac.uk/pdbsum/8zdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zdc ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 4 (DBA4) [MIM:[https://omim.org/entry/612527 612527]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:17647292</ref> <ref>PMID:19061985</ref>
== Function ==
[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Beckmann R]]
[[Category: Cheng J]]
[[Category: Huang Z]]
[[Category: Li Y]]
[[Category: Wang M]]
Retrieved from "https://proteopedia.org/8zdc"