8ya3: Difference between revisions
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==Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) treated with DTT== | |||
<StructureSection load='8ya3' size='340' side='right'caption='[[8ya3]], [[Resolution|resolution]] 3.27Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ya3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Geobacillus_thermodenitrificans_NG80-2 Geobacillus thermodenitrificans NG80-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YA3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.27Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ya3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ya3 OCA], [https://pdbe.org/8ya3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ya3 RCSB], [https://www.ebi.ac.uk/pdbsum/8ya3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ya3 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A4IJK8_GEOTN A4IJK8_GEOTN] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.[HAMAP-Rule:MF_01465][RuleBase:RU000537] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Geobacillus thermodenitrificans NG80-2]] | |||
[[Category: Large Structures]] | |||
[[Category: Gao N]] | |||
[[Category: Li L]] | |||
[[Category: Ma C]] | |||
[[Category: Ou X]] | |||
[[Category: Sun D]] | |||
[[Category: Wu X]] | |||
[[Category: Xu J]] | |||
Latest revision as of 18:57, 26 February 2025
Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) treated with DTT
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