9eaj: Difference between revisions
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The entry | ==Structure of nanobody AT206 in complex with the angiotensin II type I receptor (AT1R)== | ||
<StructureSection load='9eaj' size='340' side='right'caption='[[9eaj]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9eaj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelidae Camelidae], [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EAJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9eaj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9eaj OCA], [https://pdbe.org/9eaj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9eaj RCSB], [https://www.ebi.ac.uk/pdbsum/9eaj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9eaj ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN] NON RARE IN EUROPE: Essential hypertension;Renal tubular dysgenesis of genetic origin. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN] Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Camelidae]] | |||
[[Category: Escherichia coli]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Kruse AC]] | |||
[[Category: Skiba MA]] | |||
Latest revision as of 08:14, 5 March 2025
Structure of nanobody AT206 in complex with the angiotensin II type I receptor (AT1R)
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