9b2f: Difference between revisions
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==Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NAD+== | |||
<StructureSection load='9b2f' size='340' side='right'caption='[[9b2f]], [[Resolution|resolution]] 1.66Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9b2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9B2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9B2F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.662Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9b2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9b2f OCA], [https://pdbe.org/9b2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9b2f RCSB], [https://www.ebi.ac.uk/pdbsum/9b2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9b2f ProSAT]</span></td></tr> | ||
[[Category: Belyaeva | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/DHRS9_MOUSE DHRS9_MOUSE] 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Also plays a role in the biosynthesis of retinoic acid. Can utilize both NADH and NADPH.[UniProtKB:Q8VD48][UniProtKB:Q9BPW9] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | |||
[[Category: Belyaeva OV]] | |||
[[Category: Boeglin WE]] | |||
[[Category: Brash AR]] | |||
[[Category: Kedishvili NY]] | |||
[[Category: Newcomer ME]] | |||
[[Category: Pakhomova S]] | |||
[[Category: Popov KM]] | |||