3g8a: Difference between revisions

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<StructureSection load='3g8a' size='340' side='right'caption='[[3g8a]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='3g8a' size='340' side='right'caption='[[3g8a]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3g8a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G8A FirstGlance]. <br>
<table><tr><td colspan='2'>[[3g8a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G8A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g88|3g88]], [[3g89|3g89]], [[3g8b|3g8b]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gidB, rsmG, TTHA1971 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g8a OCA], [https://pdbe.org/3g8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g8a RCSB], [https://www.ebi.ac.uk/pdbsum/3g8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g8a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g8a OCA], [https://pdbe.org/3g8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g8a RCSB], [https://www.ebi.ac.uk/pdbsum/3g8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RSMG_THET8 RSMG_THET8]] Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. Shows a marked preference for deproteinized 16S rRNA as substrate and is completely inactive with native 30S subunits as substrate.[HAMAP-Rule:MF_00074]<ref>PMID:19622680</ref>
[https://www.uniprot.org/uniprot/RSMG_THET8 RSMG_THET8] Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. Shows a marked preference for deproteinized 16S rRNA as substrate and is completely inactive with native 30S subunits as substrate.[HAMAP-Rule:MF_00074]<ref>PMID:19622680</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/3g8a_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/3g8a_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thermus thermophilus HB8]]
[[Category: Belardinelli, R]]
[[Category: Belardinelli R]]
[[Category: Dahlberg, A E]]
[[Category: Dahlberg AE]]
[[Category: Demirci, H]]
[[Category: Demirci H]]
[[Category: Gregory, S T]]
[[Category: Gregory ST]]
[[Category: Gualerzi, C]]
[[Category: Gualerzi C]]
[[Category: Jogl, G]]
[[Category: Jogl G]]
[[Category: 16s rrna methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Rrna processing]]
[[Category: S-adenosyl-l-methionine]]
[[Category: Transferase]]
[[Category: Translation]]