Sandbox Reserved 1846: Difference between revisions
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The <scene name='10/1075246/4eb0_with_colored_ligand_stick/1'>substrate-binding site</scene> of LCC is a long, mainly hydrophobic groove that accommodates PET chains. This groove includes three subsites—designated −2, −1, and +1—that interact with specific PET units near the scissile ester bond. Hydrophobic residues such as F125, V212, M166, and F243 line the groove and facilitate binding by interacting with the aromatic rings of the PET molecule. These interactions help align the substrate in the correct position for catalysis. | The <scene name='10/1075246/4eb0_with_colored_ligand_stick/1'>substrate-binding site</scene> of LCC is a long, mainly hydrophobic groove that accommodates PET chains. This groove includes three subsites—designated −2, −1, and +1—that interact with specific PET units near the scissile ester bond. Hydrophobic residues such as F125, V212, M166, and F243 line the groove and facilitate binding by interacting with the aromatic rings of the PET molecule. These interactions help align the substrate in the correct position for catalysis. | ||
[[Image:Final rayed image of binding pocket.png|400 px|right|thumb|Figure 1]] | [[Image:Final rayed image of binding pocket.png|400 px|right|thumb|Figure 1]] | ||
<scene name='10/1075246/4eb0_surface_w_stick_ligand/1'>surface of enzyme with stick ligand</scene> | |||
== Mutation Sites of Interest == | == Mutation Sites of Interest == | ||
