9kne: Difference between revisions
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==Crystal structure of human ERRg LBD in complex with 5-nitroindole== | |||
<StructureSection load='9kne' size='340' side='right'caption='[[9kne]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9kne]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KNE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KNE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2HU:5-NITRO-1H-INDOLE'>2HU</scene>, <scene name='pdbligand=PGR:R-1,2-PROPANEDIOL'>PGR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kne OCA], [https://pdbe.org/9kne PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kne RCSB], [https://www.ebi.ac.uk/pdbsum/9kne PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kne ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu J]] | |||
[[Category: Wang N]] | |||
[[Category: Xu T]] | |||
Latest revision as of 11:29, 16 April 2025
Crystal structure of human ERRg LBD in complex with 5-nitroindole
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