Sandbox Reserved 1852: Difference between revisions

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==General Structure==
==General Structure==
[[Image:Squidbpropeller2.png|230px|left|thumb|Figure 2. Beta-propeller scaffold]]
====Scaffold====
====Scaffold====
After early Rosetta computational modelling, an ideal protein scaffold was found in the 6-bladed [https://en.wikipedia.org/wiki/Beta-propeller beta-propeller] of ''Loligo vulgalis,'' or the Europoean Squid. <ref name="Siegel"/><ref name="Scharff">PMID:11435114</ref> The protein is relatively simple, with only one chain, one unit, 324 residues, and no extra ligands, metal ions, or small molecules bound.  
After early Rosetta computational modelling, an ideal protein <scene name='10/1075254/Squidscaffold/1'>scaffold</scene> was found in the 6-bladed [https://en.wikipedia.org/wiki/Beta-propeller beta-propeller] of ''Loligo vulgalis,'' or the European Squid. <ref name="Siegel"/><ref name="Scharff">PMID:11435114</ref> The protein is relatively simple, with only one chain, one unit, 324 residues, and no extra ligands, metal ions, or small molecules bound.  


[[Image:BindingPocket.png|300px|right|thumb|Figure 3. Active site]]
[[Image:BindingPocket.png|300px|right|thumb|Figure 3. Active site]]