9ni0: Difference between revisions

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'''Unreleased structure'''


The entry 9ni0 is ON HOLD
==L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)==
 
<StructureSection load='9ni0' size='340' side='right'caption='[[9ni0]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
Authors: Fried, S.D.E., Boxer, S.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ni0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NI0 FirstGlance]. <br>
Description: L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Fried, S.D.E]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ni0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ni0 OCA], [https://pdbe.org/9ni0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ni0 RCSB], [https://www.ebi.ac.uk/pdbsum/9ni0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ni0 ProSAT]</span></td></tr>
[[Category: Boxer, S.G]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYR_ECOL6 DYR_ECOL6] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Boxer SG]]
[[Category: Fried SDE]]

Latest revision as of 05:34, 23 April 2025

L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)

9ni0, resolution 1.51Å

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