Sandbox323: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 41: | Line 41: | ||
=== Structural Analysis === | === Structural Analysis === | ||
Right-hand SPRITE analysis revealed 4Q7Q exhibited residues like those seen from enzymes operating with acetyl-like substrates.<ref name="SPRITE /> Specifically, residues Ser. 30, Gly. 69, Asn. 97, Asp. 251, and His. 254 on the A and B chains of 4Q7Q line up with similarly positioned residues on esterases like Platelet-Activating Factor Acetylhyd (PAFA), which exhibited an RMSD of 0.25 angstroms when compared to 4Q7Q.<ref name="SPRITE" /> | Right-hand SPRITE analysis revealed 4Q7Q exhibited residues like those seen from enzymes operating with acetyl-like substrates.<ref name="SPRITE" /> Specifically, residues Ser. 30, Gly. 69, Asn. 97, Asp. 251, and His. 254 on the A and B chains of 4Q7Q line up with similarly positioned residues on esterases like Platelet-Activating Factor Acetylhyd (PAFA), which exhibited an RMSD of 0.25 angstroms when compared to 4Q7Q.<ref name="SPRITE" /> | ||
[[Image:4Q7QPAFASPRITE.png|300px|right|thumb|SPRITE-based alignment between motifs from 4Q7Q and PAFA.<ref name="SPRITE" />.]] | [[Image:4Q7QPAFASPRITE.png|300px|right|thumb|SPRITE-based alignment between motifs from 4Q7Q and PAFA.<ref name="SPRITE" />.]] | ||