User:Adam Davis/Sandbox 1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Adam Davis (talk | contribs) No edit summary |
Adam Davis (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
==PPARδ Bound to GW074== | ==PPARδ Bound to GW074== | ||
Peroxisome proliferator activated receptors are ligand-activated transcription factors that regulate metabolism of lipids and glucose. They are divided into three families: α, γ, and δ. Activation of PPARδ | Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors that regulate metabolism of lipids and glucose. They are divided into three families: α, γ, and δ. Activation of PPARδ by endogenous ligands results in increased insulin sensitivity. (Note: In the literature, PPARδ is sometimes also called PPARβ). Synthetic PPARδ agonists hold significant promise for treatment of metabolic and cardiovascular diseases. | ||
<StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''> | <StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''> | ||
