User:Adam Davis/Sandbox 1: Difference between revisions

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==PPARδ Bound to GW074==
==PPARδ Bound to GW074==


Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors that regulate metabolism of lipids and glucose. They are divided into three families: α, γ, and δ. Activation of PPARδ by endogenous ligands results in increased insulin sensitivity. (Note: In the literature, PPARδ is sometimes also called PPARβ). Synthetic PPARδ agonists hold significant promise for treatment of metabolic and cardiovascular diseases.  
Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors that regulate metabolism. They are divided into three families: α, γ, and δ. PPARδ is activated by endogenous lipids, and plays an important role in the regulation of lipid metabolism. (Note: In the literature, PPARδ is sometimes also called PPARβ). Synthetic PPARδ agonists hold significant promise for treatment of metabolic and cardiovascular diseases.  


<StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''>
<StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''>