User:Adam Davis/Sandbox 1: Difference between revisions
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==PPARδ Bound to GW074== | ==PPARδ Bound to GW074== | ||
Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors that regulate metabolism. They are divided into three families: α, γ, and δ. PPARδ is activated by endogenous lipids, and plays an important role in the regulation of lipid metabolism. (Note: In the literature, PPARδ is sometimes also called PPARβ) | Peroxisome proliferator activated receptors (PPARs) are ligand-activated transcription factors that regulate metabolism. They are divided into three families: α, γ, and δ. PPARδ is activated by endogenous lipids, and plays an important role in the regulation of lipid metabolism. Synthetic PPARδ agonists hold significant promise for treatment of metabolic and cardiovascular diseases. (Note: In the literature, PPARδ is sometimes also called PPARβ). | ||
<StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''> | <StructureSection load='3tkm' size='340' side='right' caption='PDB ID: 3TKM' scene=''> | ||
