9dum: Difference between revisions
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==Human PELP1-WDR18-TEX10 complex== | |||
<StructureSection load='9dum' size='340' side='right'caption='[[9dum]], [[Resolution|resolution]] 3.56Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9dum]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DUM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.56Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dum OCA], [https://pdbe.org/9dum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dum RCSB], [https://www.ebi.ac.uk/pdbsum/9dum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dum ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/WDR18_HUMAN WDR18_HUMAN] Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211). May play a role during development (By similarity).[UniProtKB:Q68EI0]<ref>PMID:21326211</ref> <ref>PMID:22872859</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Huang J]] | |||
[[Category: Tong L]] | |||
