8r4n: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "8r4n" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of neutralizing Fab Eq4.Dp46-3A from equine antivenom bound to short chain three finger alpha-neurotoxin from Dendroaspis polylepis.== | |||
<StructureSection load='8r4n' size='340' side='right'caption='[[8r4n]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8r4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_polylepis Dendroaspis polylepis] and [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R4N FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r4n OCA], [https://pdbe.org/8r4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r4n RCSB], [https://www.ebi.ac.uk/pdbsum/8r4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r4n ProSAT]</span></td></tr> | ||
[[Category: Wibmer | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/3S11_DENPO 3S11_DENPO] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dendroaspis polylepis]] | |||
[[Category: Equus caballus]] | |||
[[Category: Large Structures]] | |||
[[Category: Wibmer CK]] | |||
Latest revision as of 05:22, 28 May 2025
Crystal structure of neutralizing Fab Eq4.Dp46-3A from equine antivenom bound to short chain three finger alpha-neurotoxin from Dendroaspis polylepis.
| ||||||||||||
