9fcp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9fcp is ~~ON HOLD until Paper Publication~~

==OPR3 loop swap variant L6(AchrOYE4) in complex with NADH4==

~~Authors~~: ~~Bijelic~~, A., ~~Kerschbaumer~~, B., ~~Macheroux~~, P.

== Structural highlights ==

<table><tr><td colspan='2'>[[9fcp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_sp._JA81 Achromobacter sp. JA81] and [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FCP OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9FCP FirstGlance].

~~Description~~: ~~OPR3 loop swap variant L6~~(~~AchrOYE4~~) in ~~complex with NADH4~~

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=WI6:[[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{S})-3-aminocarbonyl-3,6-dihydro-2~{H}-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{S},3~{R},4~{S},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+hydrogen+phosphate'>WI6</scene></td></tr>

[[Category: ~~Macheroux, P~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9fcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fcp OCA], [https://pdbe.org/9fcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fcp RCSB], [https://www.ebi.ac.uk/pdbsum/9fcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fcp ProSAT]</td></tr>

[[Category: Bijelic, A]]

</table>

[[Category: Kerschbaumer, B]]

== Function ==

[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.[https://www.uniprot.org/uniprot/I3V5V6_9BURK I3V5V6_9BURK]

__TOC__

</StructureSection>

[[Category: Achromobacter sp. JA81]]

[[Category: Large Structures]]

[[Category: Solanum lycopersicum]]

[[Category: Bijelic A]]

[[Category: Kerschbaumer B]]

[[Category: Macheroux P]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9fcp is ON HOLD  until Paper Publication
+==OPR3 loop swap variant L6(AchrOYE4) in complex with NADH4==
+<StructureSection load='9fcp' size='340' side='right'caption='[[9fcp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Bijelic, A., Kerschbaumer, B., Macheroux, P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9fcp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_sp._JA81 Achromobacter sp. JA81] and [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FCP FirstGlance]. <br>
-Description: OPR3 loop swap variant L6(AchrOYE4) in complex with NADH4
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=WI6:[[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{S})-3-aminocarbonyl-3,6-dihydro-2~{H}-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{S},3~{R},4~{S},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+hydrogen+phosphate'>WI6</scene></td></tr>
-[[Category: Macheroux, P]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fcp OCA], [https://pdbe.org/9fcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fcp RCSB], [https://www.ebi.ac.uk/pdbsum/9fcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fcp ProSAT]</span></td></tr>
-[[Category: Bijelic, A]]
+</table>
-[[Category: Kerschbaumer, B]]
+== Function ==
+[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.[https://www.uniprot.org/uniprot/I3V5V6_9BURK I3V5V6_9BURK]
+__TOC__
+</StructureSection>
+[[Category: Achromobacter sp. JA81]]
+[[Category: Large Structures]]
+[[Category: Solanum lycopersicum]]
+[[Category: Bijelic A]]
+[[Category: Kerschbaumer B]]
+[[Category: Macheroux P]]