9fnv: Difference between revisions

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'''Unreleased structure'''


The entry 9fnv is ON HOLD  until Paper Publication
==Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH12163==
 
<StructureSection load='9fnv' size='340' side='right'caption='[[9fnv]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9fnv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FNV FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1IEJ:2-(2-pyridin-3-yl-1~{H}-indol-3-yl)ethanamine'>A1IEJ</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fnv OCA], [https://pdbe.org/9fnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fnv RCSB], [https://www.ebi.ac.uk/pdbsum/9fnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fnv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OGG1_MOUSE OGG1_MOUSE] DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Davies JR]]
[[Category: Scaletti E]]
[[Category: Stenmark P]]
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