7fin: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==== | ==Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs complex== | ||
<StructureSection load='7fin' size='340' side='right'caption='[[7fin]]' scene=''> | <StructureSection load='7fin' size='340' side='right'caption='[[7fin]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fin]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FIN FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fin OCA], [https://pdbe.org/7fin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fin RCSB], [https://www.ebi.ac.uk/pdbsum/7fin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fin ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=GGL:GAMMA-L-GLUTAMIC+ACID'>GGL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fin OCA], [https://pdbe.org/7fin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fin RCSB], [https://www.ebi.ac.uk/pdbsum/7fin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fin ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
==See Also== | |||
*[[Glucose-dependent Insulinotropic Polypeptide Receptor|Glucose-dependent Insulinotropic Polypeptide Receptor]] | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bos taurus]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: Synthetic construct]] | |||
[[Category: Chang RL]] | |||
[[Category: Chen LN]] | |||
[[Category: Chen Y]] | |||
[[Category: Cong ZT]] | |||
[[Category: Dai AT]] | |||
[[Category: Feng WB]] | |||
[[Category: Hang KN]] | |||
[[Category: Liang AY]] | |||
[[Category: Ming QQ]] | |||
[[Category: Wang M]] | |||
[[Category: Wang MW]] | |||
[[Category: Wu BL]] | |||
[[Category: Xia T]] | |||
[[Category: Xu HE]] | |||
[[Category: Xu PY]] | |||
[[Category: Yang DH]] | |||
[[Category: Zhang C]] | |||
[[Category: Zhang Y]] | |||
[[Category: Zhao Fh]] | |||
[[Category: Zhao LH]] | |||
[[Category: Zhou QT]] | |||
[[Category: Zou XY]] | |||
