9jbx: Difference between revisions
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==P5A-ATPase ATP13A1 in E1P state== | |||
<StructureSection load='9jbx' size='340' side='right'caption='[[9jbx]], [[Resolution|resolution]] 3.87Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9jbx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JBX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.87Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jbx OCA], [https://pdbe.org/9jbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jbx RCSB], [https://www.ebi.ac.uk/pdbsum/9jbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jbx ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AT131_HUMAN AT131_HUMAN] Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum (PubMed:32973005, PubMed:36264797). Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane (PubMed:32973005). Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains (PubMed:32973005).<ref>PMID:32973005</ref> <ref>PMID:36264797</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Li Y]] | |||
[[Category: Liao J]] | |||
