9cv4: Difference between revisions
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==Crystal structure of the metallo-beta-lactamase VIM-31 with D-captopril== | |||
<StructureSection load='9cv4' size='340' side='right'caption='[[9cv4]], [[Resolution|resolution]] 1.36Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9cv4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CV4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MCO:1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC+ACID'>MCO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cv4 OCA], [https://pdbe.org/9cv4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cv4 RCSB], [https://www.ebi.ac.uk/pdbsum/9cv4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cv4 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/I3RJZ3_ENTCL I3RJZ3_ENTCL] Class B beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, cephalosporins and carbapenems. Acts via hydrolysis of the beta-lactam ring. Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities.[ARBA:ARBA00055160] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Enterobacter cloacae]] | |||
[[Category: Large Structures]] | |||
[[Category: Nix JC]] | |||
[[Category: Page RC]] | |||
[[Category: Silwal SB]] | |||
Latest revision as of 05:23, 3 July 2025
Crystal structure of the metallo-beta-lactamase VIM-31 with D-captopril
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