6hyp: Difference between revisions

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<SX load='6hyp' size='340' side='right' viewer='molstar' caption='[[6hyp]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
<SX load='6hyp' size='340' side='right' viewer='molstar' caption='[[6hyp]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6hyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HYP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6HYP FirstGlance]. <br>
<table><tr><td colspan='2'>[[6hyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HYP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDN1, REA1, YLR106C, L2901, L8004.13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hyp OCA], [https://pdbe.org/6hyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hyp RCSB], [https://www.ebi.ac.uk/pdbsum/6hyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hyp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6hyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hyp OCA], [http://pdbe.org/6hyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hyp RCSB], [http://www.ebi.ac.uk/pdbsum/6hyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hyp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDN1_YEAST MDN1_YEAST] Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus. Mediates ATP-dependent remodeling of the pre-ribosome just prior to export to allow maturation of 60S subunits into export-competent particles. Removes the ribosome biogenesis factor RSA4 from pre-60S ribosomal subunits in the nucleoplasm to drive nuclear export of the subunit. Involved in 3' processing of the 5.8S rRNA.<ref>PMID:15260980</ref> <ref>PMID:15528184</ref> <ref>PMID:19737519</ref> <ref>PMID:20542003</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boland, A]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Busselez, J]]
[[Category: Boland A]]
[[Category: Fagiewicz, R]]
[[Category: Busselez J]]
[[Category: Papai, G]]
[[Category: Fagiewicz R]]
[[Category: Schmidt, H]]
[[Category: Papai G]]
[[Category: Sosnowski, P]]
[[Category: Schmidt H]]
[[Category: Urnavicius, L]]
[[Category: Sosnowski P]]
[[Category: Aaa+ protein]]
[[Category: Urnavicius L]]
[[Category: Mdn1]]
[[Category: Midasin]]
[[Category: Molecular machine]]
[[Category: Motor protein]]
[[Category: Rea1]]
[[Category: Ribosome maturation]]
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