9u9c: Difference between revisions
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==Crystal structure of NDM-1 in complex with hydrolyzed amoxicillin== | |||
<StructureSection load='9u9c' size='340' side='right'caption='[[9u9c]], [[Resolution|resolution]] 1.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9u9c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U9C FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EOR:(2~{R},4~{S})-2-[(1~{R})-1-[[(2~{R})-2-azanyl-2-(4-hydroxyphenyl)ethanoyl]amino]-2-oxidanyl-2-oxidanylidene-ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic+acid'>A1EOR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: Liu | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u9c OCA], [https://pdbe.org/9u9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u9c RCSB], [https://www.ebi.ac.uk/pdbsum/9u9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u9c ProSAT]</span></td></tr> | ||
[[Category: Shi | </table> | ||
[[Category: Zhang | == Function == | ||
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Klebsiella pneumoniae]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu W]] | |||
[[Category: Shi X]] | |||
[[Category: Zhang Q]] | |||
Latest revision as of 16:30, 9 July 2025
Crystal structure of NDM-1 in complex with hydrolyzed amoxicillin
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