9e9b: Difference between revisions
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==Crystal structure of L. monocytogenes MenD with Mg2+ and ThDP bound== | |||
<StructureSection load='9e9b' size='340' side='right'caption='[[9e9b]], [[Resolution|resolution]] 2.61Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9e9b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_10403S Listeria monocytogenes 10403S]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9E9B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9e9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e9b OCA], [https://pdbe.org/9e9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e9b RCSB], [https://www.ebi.ac.uk/pdbsum/9e9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e9b ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A0H3GD77_LISM4 A0A0H3GD77_LISM4] Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).[HAMAP-Rule:MF_01659] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Listeria monocytogenes 10403S]] | |||
[[Category: Allison TM]] | |||
[[Category: Given FM]] | |||
[[Category: Ho NAT]] | |||
[[Category: Johnston JM]] | |||
[[Category: Klein M]] | |||