9oms: Difference between revisions
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==X-ray structure of human acetylcholinesterase (hAChE) in complex with bis-oxime reactivator LG-1922== | |||
<StructureSection load='9oms' size='340' side='right'caption='[[9oms]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9oms]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OMS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CD5:(2~{E})-2-hydroxyimino-~{N}-[3-[(3~{S})-3-[2-(2-hydroxyiminoethanoylamino)ethyl]piperidin-1-yl]propyl]ethanamide'>A1CD5</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9oms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9oms OCA], [https://pdbe.org/9oms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9oms RCSB], [https://www.ebi.ac.uk/pdbsum/9oms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9oms ProSAT]</span></td></tr> | ||
[[Category: Kovalevsky | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gerlits O]] | |||
[[Category: Kovalevsky A]] | |||
[[Category: Radic Z]] | |||
Latest revision as of 05:49, 30 July 2025
X-ray structure of human acetylcholinesterase (hAChE) in complex with bis-oxime reactivator LG-1922
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