9ccf: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~9ccf~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal Structure of DA7-2==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9ccf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CCF FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4Å</td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ccf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ccf OCA], [https://pdbe.org/9ccf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ccf RCSB], [https://www.ebi.ac.uk/pdbsum/9ccf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ccf ProSAT]</span></td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/PDYN_HUMAN PDYN_HUMAN] Spinocerebellar ataxia type 23. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/PDYN_HUMAN PDYN_HUMAN] Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity). Leumorphin has a typical opiod activity and may have anti-apoptotic effect.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Synthetic construct]]

[[Category: Baker D]]

[[Category: Bera AK]]

[[Category: Kang A]]

[[Category: Wu K]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9ccf is ON HOLD  until Paper Publication
+==Crystal Structure of DA7-2==
+<StructureSection load='9ccf' size='340' side='right'caption='[[9ccf]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9ccf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CCF FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ccf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ccf OCA], [https://pdbe.org/9ccf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ccf RCSB], [https://www.ebi.ac.uk/pdbsum/9ccf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ccf ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/PDYN_HUMAN PDYN_HUMAN] Spinocerebellar ataxia type 23. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/PDYN_HUMAN PDYN_HUMAN] Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity).  Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity).  Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Baker D]]
+[[Category: Bera AK]]
+[[Category: Kang A]]
+[[Category: Wu K]]