9ht1: Difference between revisions

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'''Unreleased structure'''


The entry 9ht1 is ON HOLD  until Paper Publication
==A novel bottom-up approach to find lead-compounds in billion-sized libraries==
 
<StructureSection load='9ht1' size='340' side='right'caption='[[9ht1]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ht1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HT1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HT1 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1IXE:1-(2,8-dioxa-5-azaspiro[3.6]decan-5-yl)-2-[[5-methyl-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone'>A1IXE</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ht1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ht1 OCA], [https://pdbe.org/9ht1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ht1 RCSB], [https://www.ebi.ac.uk/pdbsum/9ht1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ht1 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
== Function ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Barril X]]
[[Category: Bertran-Mostazo A]]
[[Category: Defelipe L]]
[[Category: Garcia Alai M]]
[[Category: Juarez-Jimenez J]]
[[Category: Ruiz Carrillo D]]
[[Category: Serrano-Morras A]]
Retrieved from "https://proteopedia.org/9ht1"